Archive for March, 2008
GSK ends its antifolate drugs Lapdap and Dacart
0 Comments Published by naman March 5th, 2008 in Drug resistance, TreatmentGlaxoSmithKline pulled Lapdap (chloroproguanil-dapsone) from the market and ended the development of Dacart (Lapdap+artesunate) after phase III trials of the drugs showed significant hemoglobin reductions in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. Patient’s with G6PD deficiency have weaker red blood cell membranes which can rupture when exposed to oxidative stress caused by certain drugs [...]
My goal for the blog is to achieve one post every day. Clearly, I’ve missed that mark, blogging while traveling is a trick which might take me some time to master. Until then, my apologies for any lapses in news and comments. Last week Nature carried a commentary from Mark Grabowsky, malaria manager at the [...]
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Longer entries are truncated. Click the headline of an entry to read it in its entirety.Latest
- Measuring malaria incidence
- More on the not-so-Affordable Medicines Facility for malaria
- Zanzibar is a small island of 1.2 million people
- Stage-specific actions of antimalarial drugs
- A needed review on parasite clearance
- New results for intermittant preventative therapy in children
- Patent thickets in malaria vaccine development
- Some great Ronald Ross quotes
- Wall Street Journal book review: Lifeblood
- Lasker award to Dr Tu Youyou for the development of artemisinin therapy
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Categories
- Advocacy (8)
- Blogroll (6)
- Book review (1)
- Climate (2)
- Communication (13)
- Delivery (9)
- Diagnosis (5)
- Drug resistance (13)
- Heroes (6)
- History (11)
- Operations (4)
- Policy (19)
- Random (11)
- Research (13)
- Surveillance (7)
- Treatment (18)
- Vaccine (5)
- Vector control (8)
- WHO (6)
