Archive for March, 2008

GSK ends its antifolate drugs Lapdap and Dacart

0 Comments Published by naman March 5th, 2008 in Drug resistance, Treatment

GlaxoSmithKline pulled Lapdap (chloroproguanil-dapsone) from the market and ended the development of Dacart (Lapdap+artesunate) after phase III trials of the drugs showed significant hemoglobin reductions in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. Patient’s with G6PD deficiency have weaker red blood cell membranes which can rupture when exposed to oxidative stress caused by certain drugs [...]

The billion dollar effort against malaria

0 Comments Published by naman March 4th, 2008 in Policy

My goal for the blog is to achieve one post every day. Clearly, I’ve missed that mark, blogging while traveling is a trick which might take me some time to master. Until then, my apologies for any lapses in news and comments.
Last week Nature carried a commentary from Mark Grabowsky, malaria manager at the Global [...]

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